Isto Biologics

Focused on Helping Patients Heal Faster™

 

Featured Biologic Solutions for Today’s Surgical Challenges.

 

Isto Biologics is a leading biologics and cellular therapy company. Focused on Helping Patients Heal Faster™ through innovative solutions for bone regeneration and cell-based therapies, Isto prides itself on providing the most complete and innovative biologics offerings on the market. From its inception around Isto’s flagship autologous cellular solution, the Magellan® Autologous Platelet Separator, Isto has grown through developing complete bone grafting options touching all categories of bone grafts; InQu® Bone Graft Extender & Substitute; Influx™ Advanced Allograft Technology, including Fibrant™ Functional Allograft Constructs, SPARC Integrative Bone Matrix, and ProteiOS Allograft-Derived Proteins.

ProteiOS – Allograft-derived Proteins

 

ProteiOS is a novel, patent-protected solution designed to deliver naturally derived proteins, peptides, and growth factors sourced from bone lining cells in a convenient lyophilized format. Developed to complement the surgeon’s graft of choice, ProteiOS adds meaningful biologic signaling to support bone healing, particularly in challenging fusion environments.

SPARC – Integrative Bone Matrix

SPARC is a next-generation Integrative Bone Matrix designed to combine viable cells with preserved native growth factors within a DBM fiber scaffold. The result is a cohesive graft that supports the biological components involved in bone formation while offering optimized handling and ease of use in the operating room.

Fibrant – Proprietary Functional Graft Forms

 

The Fibrant platform uses a proprietary process to transform 100% cortical allograft fibers into functional graft constructs with unique handling characteristics. These unique solutions are designed to support graft containment, delivery, and procedural versatility across a variety of spinal applications.

Fibrant Pak

A 100% cortical bone containment system designed to hold autograft or other graft materials in place while also contributing to and supporting the fusion environment.

Fibrant Liberty

A dry mixture of cortical fibers and mineralized cortical cancellous chips designed for rapid, on-demand hydration. Once hydrated, Liberty becomes a pliable graft that can be molded, packed, or shaped to match the surgical site.

Fibrant Anchor

A cortical fiber fixation sleeve designed to support pedicle screw fixation in compromised bone.

Fibrant Boat

A graft containment construct made from 100% cortical allograft designed to be loaded with autograft or other graft materials.

Fibrant Strip

A flexible construct made from 100% cortical allograft fibers designed to span longer spinal segments and support graft placement in the posterolateral fusion space.

Fibrant Wrap

A flexible sheet composed of 100% cortical allograft designed to envelop graft material for containment, bulking, or onlay applications.

Fibrant Bullet

Compressed cortical fibers engineered to expand upon hydration and conform to the surgical site. Anchor facilitates minimally invasive graft delivery while expanding to fill irregular defects.

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